# Integrated Functional Mapping and Molecular Profiling of Cell Ensembles Encoding the Effects of Addictive Substances in Rodents (R01 Clinical Trial Not Allowed)

Source: https://welltoldgrants.com/grants/rfa-da-25-023-integrated-functional-mapping-and-molecular-profiling-of/  
Official notice: https://www.grants.gov/search-results-detail/351361

> National Institutes of Health offered grants of up to $700,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on February 12, 2025.

| Field | Value |
|---|---|
| Opportunity number | RFA-DA-25-023 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | February 12, 2025 |
| Award ceiling | $700,000 |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | not stated |
| Cost sharing | not required |
| Assistance Listings | 93.279 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

## What the grant funds

This notice of funding opportunity (NOFO) aims to support research programs that adopt innovative scalable technologies to inventory, register and molecularly profile distributed cell ensembles encoding the effects of addictive substances, across various stages of exposure (acute, chronic, withdrawal, abstinence, relapse). Emphasis is on approaches capable of integrating data generated through population-scale measurements of cellular activity dynamics in behaving rodents, with other granular data modalities, collected from the same cells at single-cell resolution, such as transcriptomic class, epigenetic state, connectivity and spatial localization. The overarching goal is to deliver reference multimodal datasets thatwillinform new descriptive and predictive models of how neuronal ensembles encode addiction-associated neurobehavioral states.

## Questions people ask

### Is RFA-DA-25-023 still open?

No. It closed on February 12, 2025.

### Who can apply for Integrated Functional Mapping and Molecular Profiling of Cell Ensembles Encoding the Effects of Addictive Substances in Rodents (R01 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Integrated Functional Mapping and Molecular Profiling of Cell Ensembles Encoding the Effects of Addictive Substances in Rodents (R01 Clinical Trial Not Allowed)?

Closed February 12, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

Awards of up to $700,000 each.

### Who has been funded under RFA-DA-25-023?

NIH RePORTER lists 2 projects funded under RFA-DA-25-023 in fiscal 2025 to 2026, at 2 institutions. The most were at Medical University of South Carolina, Vanderbilt University.

### Who has won Drug Use and Addiction Research Programs grants before?

The largest recipients over five fiscal years were Yale Univ, The Johns Hopkins University, University of California, San Diego. The program made 5,071 awards worth $7.3 billion in that time.
