# PrEP for HIV Prevention among Substance Using Populations (R01 - Clinical Trial Optional)

Source: https://welltoldgrants.com/grants/rfa-da-22-017-prep-for-hiv-prevention-among-substance-using-populations/  
Official notice: https://www.grants.gov/search-results-detail/334208

> National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expected to make $2.0 million in total. Applications closed on November 12, 2021.

| Field | Value |
|---|---|
| Opportunity number | RFA-DA-22-017 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | November 12, 2021 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | $2.0 million |
| Cost sharing | not required |
| Assistance Listings | 93.279 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

## What the grant funds

NIDA is interested in research that addresses research gaps related to PrEP and its use among substance users, with the goals of improving PrEP management and implementation. Current US Public Health Service PrEP guidelines recommend PrEP for people who inject drugs (PWID) and mention alcohol and illicit drug use as potential concerns for clinical management. Only one clinical trial has evaluated PrEP among PWID and systematic data regarding the broader use of PrEP among substance users are limited. There is a need to better understand the effects of substance use on PrEP effectiveness and better inform PrEP implementation among substance users. More systematic data are needed regarding the impact of substance use on PrEP management and adherence, along with investigating potential unintended consequences of PrEP use that may be unique to substance users. This RFA is restricted to projects conducted in the United States, although foreign components are permitted where they support domestic research in the United States. Applications are encouraged that propose research in states and counties identified in the US Governments Ending the HIV Epidemic (EtHE) initiative as described here: Ending the HIV Epidemic: A Plan for America https://www.hiv.gov/federal-response/ending-the-hiv-epidemic/overview. Applications to work in locales that are not included in the EtHE initiative must provide an epidemiologic justification for their inclusion in the research.

## Questions people ask

### Is RFA-DA-22-017 still open?

No. It closed on November 12, 2021.

### Who can apply for PrEP for HIV Prevention among Substance Using Populations (R01 - Clinical Trial Optional)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for PrEP for HIV Prevention among Substance Using Populations (R01 - Clinical Trial Optional)?

Closed November 12, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

About $2.0 million in total.

### Who has been funded under RFA-DA-22-017?

NIH RePORTER lists 2 projects funded under RFA-DA-22-017 in fiscal 2022 to 2025, at 2 institutions. The most were at Friends Research Institute, Inc., University of California, San Diego.

### Who has won Drug Use and Addiction Research Programs grants before?

The largest recipients over five fiscal years were Yale Univ, The Johns Hopkins University, University of California, San Diego. The program made 5,071 awards worth $7.3 billion in that time.