# The Role of the Innate Immune System in the Pathogenesis of Type 1 Diabetes

Source: https://welltoldgrants.com/grants/rfa-ai-28-029-the-role-of-the-innate-immune-system-in/  
Official notice: https://www.grants.gov/search-results-detail/363943

> National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expects to make about 7 awards worth $15.0 million in total. It is a forecast: the notice is expected around July 15, 2027, with applications due around October 13, 2027.

| Field | Value |
|---|---|
| Opportunity number | RFA-AI-28-029 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | expected October 13, 2027 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | 7 |
| Total funding | $15.0 million |
| Cost sharing | not required |
| Assistance Listings | 93.855 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

## What the grant funds

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by utilizing Special Statutory Funding Program for Type 1 Diabetes Research funds to support studies focused on the involvement of the innate immune system in the initiation of Type 1 diabetes (T1D). This initiative directly aligns with the first goal of the congressionally mandated Special Diabetes Program, which is to identify the genetic and environmental causes of T1D. By engaging multidisciplinary teams with expertise in innate immunity and beta-cell biology, the program aims to elucidate how innate immune components interact with pancreatic tissues and beta cells. The program will leverage the use of new approach methodologies (NAMs) to precisely define the timing and impact of environmental perturbations that activate innate immune pathways. Ultimately, these studies may enable earlier identification of individuals at elevated risk for T1D (beyond genetic susceptibility) and lay the groundwork for future prevention and therapeutic strategies. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

## Questions people ask

### Who can apply for The Role of the Innate Immune System in the Pathogenesis of Type 1 Diabetes?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for The Role of the Innate Immune System in the Pathogenesis of Type 1 Diabetes?

Expected deadline October 13, 2027. Confirm the date and time in the official notice on Grants.gov.

### How much funding is available?

About $15.0 million in total across about 7 awards.