Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

Improved Drug Susceptibility Testing (DST) for Mycobacteria

Forecast Expected deadline May 28, 2027 Opportunity RFA-AI-28-018

National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expects to make about 3 awards worth $3.0 million in total. It is a forecast: the notice is expected around March 12, 2027, with applications due around May 28, 2027.

From the official notice on Grants.gov, last changed June 24, 2026. Checked October 31, 2026.

Key dates

Forecast postedJune 24, 2026
Expected postingMarch 12, 2027
Expected deadlineMay 28, 2027
Expected award dateJune 1, 2028

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Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

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Is this a realistic fit?

What the grant funds

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission by supporting research to develop improved drug susceptibility tests (DSTs) for mycobacterial drugs, including those currently used for treatment of tuberculosis (TB) and clinically important non-tuberculous mycobacterial (NTM) infections, new drugs and drugs in late-stage clinical development. TB is a leading cause of death from an infectious disease worldwide and drug-resistant strains of TB, including those resistant to new drug regimens, are increasing. In the United States, rates of NTM lung disease are rising, especially among women and older adults, while TB cases have surged to their highest level in ten years. Current assays utilize slow, culture-based processes that do not allow for the rapid testing of mycobacterial strains and their drug susceptibility. Improved DSTs are essential for guiding effective treatment, reducing drug-resistant mycobacterial rates, and preventing new transmissions. This program will support the development of innovative DST assays, including rapid genotypic and improved phenotypic methods that do not require full culture growth. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to NIAID DST (Division of Microbiology and Infectious Diseases), NIAIDDST@mail.nih.gov, Please contact via email..

Open the official notice

Questions people ask

Who can apply for Improved Drug Susceptibility Testing (DST) for Mycobacteria?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Improved Drug Susceptibility Testing (DST) for Mycobacteria?

Expected deadline May 28, 2027. Confirm the date and time in the official notice on Grants.gov.

How much funding is available?

About $3.0 million in total across about 3 awards.

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