# Artificial Intelligence in Pre-clinical Drug Development for AD/ADRD (R01 Clinical Trial Not Allowed)

Source: https://welltoldgrants.com/grants/rfa-ag-24-049-artificial-intelligence-in-pre-clinical-drug-development-for/  
Official notice: https://www.grants.gov/search-results-detail/357463

> National Institutes of Health offered grants of up to $1.0 million to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It expected to make $1.0 million in total. Applications closed on February 28, 2025.

| Field | Value |
|---|---|
| Opportunity number | RFA-AG-24-049 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | February 28, 2025 |
| Award ceiling | $1.0 million |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | $1.0 million |
| Cost sharing | not required |
| Assistance Listings | 93.866 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

## What the grant funds

This NOFO invites applications that apply existing or newly developed artificial intelligence and machine learning methods (AI/ML) to various aspects of drug discovery and preclinical drug development to accelerate the identification, optimization, and selection of preclinical drug candidates for the treatment and prevention of Alzheimers disease (AD) and AD-related dementias ADRD and increase their likelihood of success during clinical drug development. This program will also create advanced open-source analytical tools that will be made available to researchers in academia and biotech/pharma for more effective prosecution of AD/ADRD drug discovery campaigns for novel targets.

## Questions people ask

### Is RFA-AG-24-049 still open?

No. It closed on February 28, 2025.

### Who can apply for Artificial Intelligence in Pre-clinical Drug Development for AD/ADRD (R01 Clinical Trial Not Allowed)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Artificial Intelligence in Pre-clinical Drug Development for AD/ADRD (R01 Clinical Trial Not Allowed)?

Closed February 28, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

Awards of up to $1.0 million each. About $1.0 million in total.

### Who has been funded under RFA-AG-24-049?

NIH RePORTER lists 5 projects funded under RFA-AG-24-049 in fiscal 2026, at 5 institutions. The most were at Trustees of Indiana University, Univ of North Carolina Chapel Hill, Purdue University.

### Who has won Aging Research grants before?

The largest recipients over five fiscal years were The Regents of the University of California, San Francisco, The Trustees of Columbia University in the City of New York, University of Southern California. The program made 11,026 awards worth $19 billion in that time.