# Development and Validation of Harmonized Methodologies to Measure NAD+ and Related Metabolites in Clinical Trials (U01 Clinical Trial Required)

Source: https://welltoldgrants.com/grants/rfa-ag-24-039-development-and-validation-of-harmonized-methodologies-to/  
Official notice: https://www.grants.gov/search-results-detail/349106

> National Institutes of Health offered grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications closed on November 2, 2023.

| Field | Value |
|---|---|
| Opportunity number | RFA-AG-24-039 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | November 2, 2023 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | not stated |
| Cost sharing | not required |
| Assistance Listings | 93.866 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

## What the grant funds

This Notice of Funding Opportunity (NOFO) invites applications to develop and validate the standardized protocols for measuring nicotinamide adenine dinucleotide (NAD+) and related metabolites levels in humans, including sample collection and storage, assays calibration, and standardization of measurements across different types of samples such as plasma, tissue, or serum extracts, and validation of these protocols. Limited preclinical animal studies could be proposed by the applicants, if such studies are integral part of the applications and if they are needed to test the select elements of the standardized protocols in animal models before such protocols could be tested in humans. The proposed studies will be funded by individual awards, but the awardees will be required to interact as a network to exchange information, discuss their progress, pitfalls and issues arising during studies implementation.

## Questions people ask

### Is RFA-AG-24-039 still open?

No. It closed on November 2, 2023.

### Who can apply for Development and Validation of Harmonized Methodologies to Measure NAD+ and Related Metabolites in Clinical Trials (U01 Clinical Trial Required)?

National Institutes of Health accepted applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Development and Validation of Harmonized Methodologies to Measure NAD+ and Related Metabolites in Clinical Trials (U01 Clinical Trial Required)?

Closed November 2, 2023. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### Who has been funded under RFA-AG-24-039?

NIH RePORTER lists 2 projects funded under RFA-AG-24-039 in fiscal 2024 to 2026, at 2 institutions. The most were at University of Pennsylvania, Brigham and Women's Hospital.

### Who has won Aging Research grants before?

The largest recipients over five fiscal years were The Regents of the University of California, San Francisco, The Trustees of Columbia University in the City of New York, University of Southern California. The program made 11,026 awards worth $19 billion in that time.