Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)

Forecast Expected deadline September 7, 2027 Opportunity PAS-28-073

National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It is a forecast: the notice is expected around July 7, 2027, with applications due around September 7, 2027.

From the official notice on Grants.gov, last changed October 1, 2026. Checked October 31, 2026.

Key dates

Forecast postedOctober 1, 2026
Expected postingJuly 7, 2027
Expected deadlineSeptember 7, 2027
Expected award dateMarch 1, 2028

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Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

This Notice of Funding Opportunity (NOFO) uses a R61/R33 Phased Innovation Award to support milestone-driven research that advances innovative HIV prevention interventions from development and feasibility testing to larger-scale efficacy, effectiveness, implementation, and dissemination studies. The R61 phase will support the development, refinement, adaptation, and pilot testing of novel or enhanced HIV prevention and treatment strategies, including studies designed to address key scientific, operational, or implementation questions necessary to establish feasibility and readiness for larger-scale evaluation. Projects may generate evidence needed to optimize intervention design, delivery, and implementation in diverse populations and settings. The R33 phase will support expanded testing of interventions and implementation strategies that have successfully met R61 milestones. Studies may evaluate effectiveness, implementation, scalability, sustainability, clinical management, or delivery of HIV prevention interventions that include integrated approaches addressing alcohol use and related comorbidities.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to HIV/AIDS and Alcohol Research Program, NIAAA-HIV@nih.gov, 301-402-0332.

Open the official notice

Questions people ask

Who can apply for HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)?

Expected deadline September 7, 2027. Confirm the date and time in the official notice on Grants.gov.

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