Grants / Department of Health and Human Services / National Institutes of Health

Undiagnosed Diseases Network (UDN) Clinical Networks of Diagnostic Excellence

Forecast Expected deadline May 25, 2027 Opportunity PAR-27-137

• Award ceilingnot stated
• Award floornot stated
• Expected awardsnot stated
• Total fundingnot stated
• Cost sharingNot required
• Funding typeCooperative Agreement

Key dates

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Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities/Indian housing authorities
• Native American tribal organizations (other than Federally recognized tribal governments)
• Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
• Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
• Private institutions of higher education
• For profit organizations other than small businesses
• Small businesses
• Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

• No cost sharing or match is required.

What the grant funds

NINDS intends to support multiple clinical Networks of Diagnostic Excellence (NODEs) as part of the next phase of the Undiagnosed Diseases Network (UDN). Unlike prior phases, clinical NODEs are expected to function as geographically distributed regional clinical networks rather than single-site centers. Each clinical NODE would establish and lead a regional network built on existing partnerships with academic medical centers, hospitals, clinics, federally qualified health centers, and other community-based clinical partners to broaden access to specialized diagnostic expertise and extend the reach of the UDN. Clinical NODEs are expected to provide a coordinated, multidisciplinary and participant-centered evaluation of individuals with highly challenging, difficult-to-diagnose conditions. In collaboration with the Network, clinical NODEs will recruit and enroll participants, conduct medical record reviews, make enrollment determinations, communicate review outcomes and recommendations to participants and referring providers, and coordinate the clinical evaluation with local partner sites and referring providers, as appropriate. In addition, clinical NODEs will participate in network collaborations to develop and test innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions, support systematic re-evaluation of unsolved UDN cases, and conduct research to optimize participant access and experience. Clinical NODEs are also expected to participate in network governance and infrastructure; provide training to support consistent implementation of UDN processes and standards; incorporate participant and community input into workflows and engagement strategies, such as through a Community Advisory Board or comparable mechanisms; and monitor site performance. Applications are not being solicited at this time. This Forecast is being published to provide potential applicants time to plan, establish collaborations, formalize regional partnerships, and prepare responsive projects.

Category: Health.

How to apply

1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to UDN Program Staff, UDNProgramStaff@ninds.nih.gov, Please contact via email..

Open the official notice