Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center

Forecast Expected deadline May 25, 2027 Opportunity PAR-27-136

National Institutes of Health plans to offer grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. It is a forecast: the notice is expected around March 25, 2027, with applications due around May 25, 2027.

From the official notice on Grants.gov, last changed September 10, 2026. Checked October 31, 2026.

Key dates

Forecast postedSeptember 10, 2026
Expected postingMarch 25, 2027
Expected deadlineMay 25, 2027
Expected award dateApril 25, 2028

Add the deadline to your calendar

Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

More grants for nonprofits, colleges and universities, state and local governments, tribes, small businesses, businesses.

Is this a realistic fit?

What the grant funds

NINDS intends to support a Diagnostic Research Innovation Center (DRIC) for the next phase of the Undiagnosed Diseases Network (UDN). The new Network is expected to include a Clinical and Data Coordinating Center (CDCC), geographically distributed clinical Networks of Diagnostic Excellence (NODEs), the NIH Undiagnosed Diseases Program (UDP), a DRIC, the UDN Foundation, patient advocacy organizations, NIH, and other stakeholders. The DRIC will contribute to the diagnosis of UDN participants, including participating in the systematic re-evaluation of unsolved UDN cases from previous phases of the UDN. The DRIC is expected to test and advance innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions. Working closely with clinical NODEs, the UDP, the CDCC, and other UDN stakeholders, the DRIC will support the generation and testing of diagnostic hypotheses including providing expertise and resources in advanced sequencing and multi-omics, gene function studies in animal and human in vitro models, and the development of non-genetic diagnostic strategies. Collaborating with the Network, the DRIC will contribute to the discovery of novel disease-associated genes and genomic variants, non-genetic contributors to UDN phenotypes, and the identification of new diseases and syndromes. Support is expected for an integrated center that brings together complementary capabilities and investigators with demonstrated scientific synergy and prior collaboration. Applications are not being solicited at this time. This Forecast is being published to provide potential applicants time to plan, establish collaborations, and develop responsive projects.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to UDN Program Staff, UDNProgramStaff@ninds.nih.gov, Please contact via e-mail..

Open the official notice

Questions people ask

Who can apply for Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center?

Expected deadline May 25, 2027. Confirm the date and time in the official notice on Grants.gov.

Similar open grants