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Grants / Department of Health and Human Services / National Institutes of Health

Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)

Open Closes September 26, 2029 (1061 days left) Opportunity PAR-27-003

National Institutes of Health is offering grants to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications close on September 26, 2029.

From the official notice on Grants.gov, last changed October 14, 2026. Checked October 31, 2026.

Key dates

PostedOctober 14, 2026
DeadlineSeptember 26, 2029
Archived by Grants.govNovember 26, 2029

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Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibilityForeign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards. Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

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Is this a realistic fit?

What the grant funds

This Notice of Funding Opportunity (NOFO) supports interdisciplinary research teams of three to six Program Directors/Principal Investigators (PDs/PIs) to address ambitious and challenging research questions. Collaborative program teams are expected to be integrated, working together to tackle a single focused scientific goal that requires considerable synergy and meaningful team interaction. Program goals should not be achievable through individual efforts or a collection of projects. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.

Category: Health.

How to apply

  1. Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to National Institutes of Health, NIGMS-TeamScience@NIH.gov, 301-402-2541.

Open the official notice

Questions people ask

Who can apply for Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)?

Closes September 26, 2029 (1061 days left). Confirm the date and time in the official notice on Grants.gov.

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