Well Told Grants

Grants / Department of Health and Human Services / National Institutes of Health

Early Immune System Development and Ontogeny (R01 Clinical Trial Optional)

Open Closes November 5, 2028 (736 days left) Opportunity PAR-25-362

National Institutes of Health is offering grants of up to $400,000 to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. Applications close on November 5, 2028.

From the official notice on Grants.gov, last changed March 19, 2026. Checked October 31, 2026.

Key dates

PostedDecember 30, 2024
DeadlineNovember 5, 2028
Archived by Grants.govDecember 5, 2028

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Who can apply

This opportunity is open to nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses.

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

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Is this a realistic fit?

What the grant funds

The purpose of this Notice of Funding Opportunity (NOFO) is tofurther elucidate the mechanisms of early immune development in utero, during the early post-natal period and during early childhood in neonates, infants, and children and adolescents with or without in-utero exposure to HIV or Anti-Retroviral Therapeutics (ART).This initiative aims to understand intricate mechanisms of immune cells at the maternal-fetal interface, T and B cell development and maturation in offspring, and local immune responses and the role of systemic immunity.

Category: Health, Income Security and Social Services.

How to apply

  1. Read the full notice and attachments on Grants.gov and the agency's announcement. The notice is the official source for deadlines and requirements.
  2. Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
  3. Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.

Questions go to National Institutes of Health, grantsinfo@nih.gov, 301-402-2541.

Open the official notice

Questions people ask

Who can apply for Early Immune System Development and Ontogeny (R01 Clinical Trial Optional)?

National Institutes of Health accepts applications from nonprofits, colleges and universities, state and local governments, tribes, small businesses and businesses. The notice adds further conditions, so read its eligibility section.

What is the deadline for Early Immune System Development and Ontogeny (R01 Clinical Trial Optional)?

Closes November 5, 2028 (736 days left). Confirm the date and time in the official notice on Grants.gov.

How much funding is available?

Awards of up to $400,000 each.

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