# NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional)

Source: https://welltoldgrants.com/grants/par-25-133-neuronext-small-business-innovation-in-clinical-trials-u44/  
Official notice: https://www.grants.gov/search-results-detail/357073

> National Institutes of Health offered grants to small businesses. Applications closed on November 17, 2025.

| Field | Value |
|---|---|
| Opportunity number | PAR-25-133 |
| Agency | National Institutes of Health |
| Status | Forecast |
| Deadline | November 17, 2025 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | not stated |
| Cost sharing | not required |
| Assistance Listings | 93.853 |

## Who can apply

- Small businesses

Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

## What the grant funds

This announcement encourages small business applications for exploratory clinical trials of investigational agents (drugs, biologics, surgical therapies or devices) that may contribute to the justification for and provide the data required for designing clinical studies. Diseases chosen for study should be based on the NINDS strategic plan and clinical research interests (www.ninds.nih.gov/funding/areas/index.htm).

## Questions people ask

### Is PAR-25-133 still open?

No. It closed on November 17, 2025.

### Who can apply for NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional)?

National Institutes of Health accepted applications from small businesses. The notice adds further conditions, so read its eligibility section.

### What is the deadline for NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional)?

Closed November 17, 2025. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### Who has won Extramural Research Programs in the Neurosciences and Neurological Disorders grants before?

The largest recipients over five fiscal years were The General Hospital Corporation, The Regents of the University of California, San Francisco, The Johns Hopkins University. The program made 8,641 awards worth $9.1 billion in that time.