# Reimagining Protein Manufacturing (RPM)

Source: https://welltoldgrants.com/grants/hr001121s0038-reimagining-protein-manufacturing-rpm/  
Official notice: https://www.grants.gov/search-results-detail/335391

> DARPA - Biological Technologies Office offered grants to the applicants described in the notice. Applications closed on November 16, 2021.

| Field | Value |
|---|---|
| Opportunity number | HR001121S0038 |
| Agency | DARPA - Biological Technologies Office |
| Status | Forecast |
| Deadline | November 16, 2021 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | not stated |
| Total funding | not stated |
| Cost sharing | not required |
| Assistance Listings | 12.910 |

## Who can apply

- Others (see text field entitled "Additional Information on Eligibility" for clarification)

All responsible sources capable of satisfying the Government's needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information.

## What the grant funds

The Reimagining Protein Manufacturing (RPM) program aims to ensure timely DoD access to critical medical countermeasures (MCMs) by establishing the foundational technologies needed for fully distributed, on-demand manufacturing of protein-based MCMs and associated raw materials. To achieve this goal, RPM will develop technologies to enable immediate synthesis (lead time approximately 24 hours) of bioactive protein MCMs and raw material production enzymes at a yield corresponding to > 500 doses per week. This technology will allow the DoD to rapidly secure access to both therapeutic proteins and enzymes needed for nucleic acid-based MCM synthesis, and reduce reliance on complex supply chains.

## Questions people ask

### Is HR001121S0038 still open?

No. It closed on November 16, 2021. A newer notice is open: DARPARA2701, closes January 13, 2027 (67 days left).

### Who can apply for Reimagining Protein Manufacturing (RPM)?

DARPA - Biological Technologies Office accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Reimagining Protein Manufacturing (RPM)?

Closed November 16, 2021. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### Who has won Research and Technology Development grants before?

The largest recipients over five fiscal years were University of Southern California, Clemson University, Massachusetts Institute of Technology. The program made 739 awards worth $1.5 billion in that time.