# Bioimaging Research Approaches for the Bioeconomy & the Environment

Source: https://welltoldgrants.com/grants/de-foa-0003231-bioimaging-research-approaches-for-the-bioeconomy-the/  
Official notice: https://www.grants.gov/search-results-detail/351379

> Office of Science offered grants of up to $2.4 million (at least $600,000) to the applicants described in the notice. It expected to make $16.0 million in total. Applications closed on March 5, 2024.

| Field | Value |
|---|---|
| Opportunity number | DE-FOA-0003231 |
| Agency | Office of Science |
| Status | Forecast |
| Deadline | March 5, 2024 |
| Award ceiling | $2.4 million |
| Award floor | $600,000 |
| Expected awards | not stated |
| Total funding | $16.0 million |
| Cost sharing | not required |
| Assistance Listings | 81.049 |

## Who can apply

- Others (see text field entitled "Additional Information on Eligibility" for clarification)

All types of domestic applicants are eligible to apply, except nonprofit organizations described in section 501(c)(4) of the Internal Revenue Code of 1986 that engaged in lobbying activities after December 31, 1995. Federally affiliated entities must adhere to the eligibility standards below: III.A.1. DOE/NNSA National Laboratories DOE/NNSA National Laboratories are not eligible to submit applications under this FOA but may be proposed as subrecipients under another organization’s application. If recommended for funding as a proposed subrecipient, the value of the proposed subaward will be removed from the prime applicant’s award and will be provided to the laboratory through the DOE Field-Work Proposal System and work will be conducted under the laboratory’s contract with DOE. No administrative provisions of this FOA will apply to the laboratory or any laboratory subcontractor. Additional instructions for securing authorization from the cognizant Contracting Officer are found in Section VIII of this FOA. III.A.2. Non-DOE/NNSA FFRDCs Non-DOE/NNSA FFRDCs are not eligible to submit applications under this FOA but may be proposed as subrecipients under another organization’s application. If recommended for funding as a proposed subrecipient, the value of the proposed subaward may be removed from the prime applicant’s award and may be provided through an interagency agreement to the FFRDC’s sponsoring Federal Agency. Additional instructions for securing authorization from the cognizant Contracting Officer are found in Section VIII of this FOA. III.A.3. Other Federal Agencies Other Federal Agencies are not eligible to submit applications under this FOA but may be proposed as subrecipients under another organization’s application. If recommended for funding as a proposed subrecipient, the value of the proposed subaward may be removed from the prime applicant’s award and may be provided through an interagency agreement. Additional instructions for providing statutory authorization are found in Section VIII of this FOA.

## What the grant funds

BER is soliciting applications in the following subtopic areas: 1) fundamental imaging or sensing research from concept to validation or 2) evaluation of biological hypotheses or questions with feasible, use-inspired prototypes. Under subtopic 1) applications could evaluate, untested concepts, and theoretical models, develop novel experimental prototypes and validate measurement accuracy against known technical or biological validation standards. Under subtopic 2) research of experimental prototypes of instruments and methods that will include demonstration of feasibility leading to hypothesis-driven biological experimentation to demonstrate value to the user community. This FOA does not solicit late-stage optimization after initial prototype research, or engineering development of resources, or equipment. Subtopic 1: Concept to Validation Projects can begin at the conceptual (pre-experimental) stage and move through validation by comparing technical performance and biological measurements against accepted standards. This stage is too early to investigate new biological questions until proven accurate and reproducible. The intent of the first subtopic is to include applications that might not yet have experimental demonstration of feasibility but hold promise of significant impact if successful. These high-risk high-reward applications might reside completely within a scientific and technical field of research and are not required to demonstrate novel biological utility. However, validation against already characterized synthetic or biological samples in BER-supported bioenergy and environmental research should be included. Measurement should be compared to known or “gold-standard” targets measured by competing methods. Demonstration in living systems is not required, but systems must have future impact on in situ imaging, measuring, or modeling for plant- and microbial-based bioenergy research. Proposed projects should hold promise for significant advances in imaging or sensing and must include plans to manage the high risk inherent in testing novel concepts and techniques. These “high-risk/high reward” projects might have no preliminary data to support the concept making feasibility challenging to evaluate for scientific merit. However, reviewers will be instructed to evaluate merit based on the future significance of the potential for success and the risk-reward balance when evaluating the applications for consideration of funding.

## Questions people ask

### Is DE-FOA-0003231 still open?

No. It closed on March 5, 2024. A newer notice is open: DE-FOA-0003673, closes January 12, 2027 (66 days left).

### Who can apply for Bioimaging Research Approaches for the Bioeconomy & the Environment?

Office of Science accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Bioimaging Research Approaches for the Bioeconomy & the Environment?

Closed March 5, 2024. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

Awards of up to $2.4 million each. About $16.0 million in total.

### Who has won Office of Science Financial Assistance Program grants before?

The largest recipients over five fiscal years were Michigan State University Foundation, General Atomics, University of Wisconsin System. The program made 6,205 awards worth $7.7 billion in that time.