# Systems Biology-Enabled Microbiome Research to Facilitate Predictions of Interactions and Behavior in the Environment

Source: https://welltoldgrants.com/grants/de-foa-0002602-systems-biology-enabled-microbiome-research-to-facilitate/  
Official notice: https://www.grants.gov/search-results-detail/336982

> Office of Science offered grants of up to $1.2 million (at least $250,000) to the applicants described in the notice. It expected to make $36.0 million in total. Applications closed on April 7, 2022.

| Field | Value |
|---|---|
| Opportunity number | DE-FOA-0002602 |
| Agency | Office of Science |
| Status | Forecast |
| Deadline | April 7, 2022 |
| Award ceiling | $1.2 million |
| Award floor | $250,000 |
| Expected awards | not stated |
| Total funding | $36.0 million |
| Cost sharing | not required |
| Assistance Listings | 81.049 |

## Who can apply

- Others (see text field entitled "Additional Information on Eligibility" for clarification)

All types of domestic applicants are eligible to apply, except nonprofit organizations described in section 501(c)(4) of the Internal Revenue Code of 1986 that engaged in lobbying activities after December 31, 1995.Federally affiliated entities must adhere to the eligibility standards below:1. DOE/NNSA National LaboratoriesDOE/NNSA National Laboratories are not eligible to submit applications under this FOA but may be proposed as subrecipients under another organization’s application. If recommended for funding as a proposed subrecipient, the value of the proposed subaward will be removed from the prime applicant’s award and will be provided to the laboratory through the DOE Field-Work Proposal System and work will be conducted under the laboratory’s contract with DOE. No administrative provisions of this FOA will apply to the laboratory or any laboratory subcontractor. Additional instructions for securing authorization from the cognizant Contracting Officer are found in Section VIII of this FOA.2. Non-DOE/NNSA FFRDCsNon-DOE/NNSA FFRDCs are not eligible to submit applications under this FOA but may be proposed as subrecipients under another organization’s application. If recommended for funding as a proposed subrecipient, the value of the proposed subaward may be removed from the prime applicant’s award and may be provided through an interagency agreement to the FFRDC’s sponsoring Federal Agency. Additional instructions for securing authorization from the cognizant Contracting Officer are found in Section VIII of this FOA.3. Other Federal AgenciesOther Federal Agencies are not eligible to submit applications under this FOA but may be proposed as subrecipients under another organization’s application. If recommended for funding as a proposed subrecipient, the value of the proposed subaward may be removed from the prime applicant’s award and may be provided through an interagency agreement. Additional instructions for providing statutory authorization are found in Section VIII of this FOA.

## What the grant funds

BER supports fundamental, interdisciplinary research to achieve a predictive systems-level understanding of Earth, environmental and biological systems. The overarching goals of the BER Program are to solve critical challenges in energy security and environmental stewardship. As part of its mission, BER invests in crosscutting technologies and programs to enable multi-scale, systems-level research to achieve a predictive understanding of systems biology, biological community function, and environmental behavior. The GSP supports research in genome biology as it relates to Bioenergy, Biosystems Design, and Environmental Microbiome Research. These three program pillars are tightly integrated across a portfolio of research projects on bioenergy, biosystems design, synthetic biology, microbiome science, sustainability, computational biology, and related topics that seeks to catalyze omics-enabled discoveries about the functional characteristics of cells, organisms, and whole biological systems. Supported research aims to enhance the nation’s energy and environmental security, and to promote basic research in the environmental and biological sciences in support of DOE’s mission. This FOA is released as part of BSSD’s Environmental Microbiome Research program element. The GSP seeks to understand microbial interactions in natural environments and how such interactions are shaped by environmental change. Understanding community responses to environmental perturbations and long-term change represents an important frontier for efforts to predict ecosystem behavior at different scales. BSSD aims at enabling such predictions by discovering how organisms and community behavior can be understood by leveraging omic-based information. In addition, many environmental microbes harbor genetic potential with relevance to bioenergy and bio-design, and a fundamental understanding of their environmental genomics is likely to have broader impacts across DOE’s mission space. More specifically, this FOA will support projects that enhance our ability to understand microbial interactions dynamically and predictively. Research should facilitate realistic recapitulations of microbial ecosystems that move beyond the characterization of microbial and genetic diversity. Of particular interest are projects that will provide insights into microbial processes that enhance the long-term storage of carbon in soils, thereby leading to net carbon removal from the atmosphere.

## Questions people ask

### Is DE-FOA-0002602 still open?

No. It closed on April 7, 2022. A newer notice is open: DE-FOA-0003673, closes January 12, 2027 (66 days left).

### Who can apply for Systems Biology-Enabled Microbiome Research to Facilitate Predictions of Interactions and Behavior in the Environment?

Office of Science accepted applications from the applicants described in the notice. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Systems Biology-Enabled Microbiome Research to Facilitate Predictions of Interactions and Behavior in the Environment?

Closed April 7, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

Awards of up to $1.2 million each. About $36.0 million in total.

### Who has won Office of Science Financial Assistance Program grants before?

The largest recipients over five fiscal years were Michigan State University Foundation, General Atomics, University of Wisconsin System. The program made 6,205 awards worth $7.7 billion in that time.