Public Health Crisis Response Cooperative Agreement
Open
Centers for Disease Control - OPHPR is offering grants of up to $5.0 million (at least $50,000) to state and local governments and tribes. It expects to make about 113 awards worth $500 million in total. Applications close on February 11, 2027.
From the official notice on Grants.gov, last changed December 20, 2024. Checked October 31, 2026.
- Award ceiling$5.0 million
- Award floor$50,000
- Expected awards113
- Total funding$500 million
- Cost sharingNot required
- Funding typeCooperative Agreement
Key dates
| Posted | January 13, 2022 |
|---|---|
| Deadline | February 11, 2027 |
| Archived by Grants.gov | March 1, 2027 |
Add the deadline to your calendar
Who can apply
This opportunity is open to state and local governments and tribes.
- State governments
- County governments
- City or township governments
- Special district governments
- Native American tribal governments (Federally recognized)
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
This NOFO is intended for states, political subdivisions of states, and other public entities as specified in section 317(a) of the Public Health Service Act (42 USC § 247(b)). It targets public health organizations that serve state, tribal, local, and territorial populations and are constitutionally empowered to protect the health and welfare of their respective communities, focused on executing emergency preparedness and response services. To demonstrate existing capacity for public health emergency management, applicants must submit their response organizational charts and work plans. If these documents are not submitted, the application will be considered non-responsive and will receive no further review. Local government organizations or their bona fide agents must:Serve a county population of 2 million or more or serve a city population of 400,000 or more. Populations for county and city jurisdictions are based on the following 2021 U.S. Census resources:City and Town Population Totals: 2020-2021 (census.gov) U.S. Census – Annual Estimates of the Resident Population for Incorporated Places, Ranked by July 1, 2021, Population: April 1, 2020, to July 1, 2021County Population Totals: 2020-2021 (census.gov) U.S. Census – Annual Estimates for 2021Sources may be updated as census data change over timeLocal jurisdictions that meet population requirements are listed in Attachment A.Tribal governments or their bona fide agents must be federally recognized and:Serve a population of 50,000 or more.CDC will reopen this announcement periodically over the five-year NOFO period to accommodate population changes and ensure we maintain a current roster of eligible jurisdictions for emergency response. Sources for future postings of this NOFO will be based on the latest census data and may change over time. The anticipated dates for reposting are noted below. Applicants will have 60 days to submit an application. July 2024July 2025July 2026
Is this a realistic fit?
- No cost sharing or match is required.
What the grant funds
CDC seeks to enhance the nation’s ability to rapidly mobilize, surge, and respond to public health emergencies (PHEs) as identified by CDC by establishing a roster of approved but unfunded (ABU) applicants that may receive rapid funding to respond to PHEs of such magnitude, complexity, or significance that they would have an overwhelming impact upon, and exceed resources available to, the jurisdictions. Applicants will undergo an objective merit review process, and entities that successfully meet the requirements for approval will be placed on the ABU list. CDC will use this ABU list for emergencies that require federal support to effectively respond to, manage, and address identified public health threats. CDC will make funding related to this NOFO available once it has determined a public health emergency exists or is considered imminent and will be contingent upon the availability and stipulations of appropriations. CDC will provide additional guidance and information to those on the ABU list when this NOFO is funded. Since this NOFO is designed to collect applications prior to a PHE, applicants are encouraged to submit work plans and budgets that demonstrate their ability to respond to a PHE. COVID-19 public health response plans, such as plans funded under CDC-RFA-TP18-1802 in 2020 are acceptable for this purpose. If this NOFO is funded for a specific PHE, CDC will develop supplemental guidance that outlines additional work plan and budget requirements tailored to the emergency. This NOFO is not a capacity-building funding mechanism, and it is not intended to create or establish new public health (PH) emergency management programs. It may be used to re- establish capacity lost or diminished because of the public health crisis. It is designed to support the surge needs of existing programs responding to a significant PHE. CDC will provide supplemental guidance to entities on the ABU list when this NOFO is activated regarding specific activities intended to address the emergency. CDC has strong relationships with governmental PH departments, community-based organizations, and other domestic partners and supports them for planning, capacity-building, preparedness, and response to PHEs. This NOFO complements these ongoing capacity-building preparedness and response programs by providing a mechanism for CDC to rapidly mobilize and fund PH organizations for specific response needs.
How to apply
- Read the full notice and attachments on Grants.gov. The notice is the official source for deadlines and requirements.
- Make sure your organization has an active SAM.gov registration and Unique Entity ID; registration can take several weeks.
- Register on Grants.gov and submit through Workspace before the deadline and time given in the notice. Our application guide walks through each step.
Questions go to Centers for Disease Control - OPHPR, DSLRCrisisCoag@cdc.gov, 7704882756.
Questions people ask
Who can apply for Public Health Crisis Response Cooperative Agreement?
Centers for Disease Control - OPHPR accepts applications from state and local governments and tribes. The notice adds further conditions, so read its eligibility section.
What is the deadline for Public Health Crisis Response Cooperative Agreement?
Closes February 11, 2027 (103 days left). Confirm the date and time in the official notice on Grants.gov.
How much funding is available?
Awards of up to $5.0 million each. About $500 million in total across about 113 awards.
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