# Informing global polio eradication efforts through innovative modeling approaches

Source: https://welltoldgrants.com/grants/cdc-rfa-gh22-2272-informing-global-polio-eradication-efforts-through/  
Official notice: https://www.grants.gov/search-results-detail/336887

> Centers for Disease Control - CGH offered grants to any type of organization. It expected to make about 2 awards worth $1.8 million in total. Applications closed on May 6, 2022.

| Field | Value |
|---|---|
| Opportunity number | CDC-RFA-GH22-2272 |
| Agency | Centers for Disease Control - CGH |
| Status | Forecast |
| Deadline | May 6, 2022 |
| Award ceiling | not stated |
| Award floor | not stated |
| Expected awards | 2 |
| Total funding | $1.8 million |
| Cost sharing | not required |
| Assistance Listings | 93.185 |

## Who can apply

- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- For profit organizations other than small businesses
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"

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## What the grant funds

The Global Polio Eradication Initiative (GPEI) began in 1988 with the objective of wild poliovirus (WPV) eradication and ultimate eradication of all polioviruses, including vaccine-derived polioviruses (VDPV). The Centers for Disease Control and Prevention (CDC) is one of the founding partners of the GPEI, providing technical and financial support (https://polioeradication.org/). Polio eradication remains an agency-wide priority; CDC's Emergency Operations Center (EOC) has been activated since December 2011 to support global polio response activities. The GPEI has made tremendous progress toward global WPV eradication, from 125 countries in 1988 to two countries in 2021. WPV types 2 and 3 have been eradicated and only WPV type 1 (WPV1) remains. Of WHO’s six Regions, only the Eastern Mediterranean Region remains affected. The GPEI faces two major challenges: 1) continued transmission of WPV1 in Pakistan and Afghanistan and 2) increasing number of circulating vaccine-derived poliovirus (cVDPVs) which result from prolonged transmission in under-immunized communities of the live weakened virus from the oral poliovirus vaccine (OPV). GPEI’s newest strategy, Polio Eradication Strategy 2022-2026: Delivering on a Promise, outlines how the partnership intends to address these challenges. Concurrently, GPEI must begin planning now for the future of a polio-free world. Current planning is that within 12 months of certification of WPV eradication, all OPVs will be removed from essential immunization programs (i.e., OPV cessation). The risk of emergence of VDPVs will be highest in the first two years after OPV cessation as intestinal mucosal immunity needed to stop virus transmission wanes. The risk of accidental introduction in communities and the environment by a containment breach from a poliovirus essential facility (PEF), such as a poliovirus vaccine manufacturer, will persist as long as live polioviruses are maintained at facilities. Numerous key questions remain about interrupting cVDPV transmission in the near-term, and the long-term needs of poliovirus surveillance. For cVDPV interruption, the focus is on which factor or combination of factors would optimize field-level response strategies to quickly interrupt transmission and associated costs. Questions on long-term surveillance needs include the optimal mix of poliovirus surveillance systems and activities that will be sustainable yet sensitive to detect emergence of VDPV and associated costs.

## Questions people ask

### Is CDC-RFA-GH22-2272 still open?

No. It closed on May 6, 2022. A newer notice is forecast: CDC-RFA-JG-27-0077, expected deadline February 12, 2027.

### Who can apply for Informing global polio eradication efforts through innovative modeling approaches?

Centers for Disease Control - CGH accepted applications from any type of organization. The notice adds further conditions, so read its eligibility section.

### What is the deadline for Informing global polio eradication efforts through innovative modeling approaches?

Closed May 6, 2022. Applications are no longer accepted; the program's newer notices are on this page when there are any.

### How much funding is available?

About $1.8 million in total across about 2 awards.

### Who has won Immunization Research, Demonstration, Public Information and Education Training and Clinical Skills Improvement Projects grants before?

The largest recipients over five fiscal years were Unicef, National Foundation for the Centers for Disease Control & Prevention, Inc., Community Catalyst Inc. The program made 243 awards worth $857 million in that time.