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The McKnight Endowment Fund for Neuroscience

Accepts applications Minneapolis, Minnesota · EIN 411563321

The McKnight Endowment Fund for Neuroscience is a private foundation in Minneapolis, Minnesota. In tax year 2024 it gave $3.2 million in 45 grants; the typical grant was $75,000 and the largest $110,310. It accepts applications; its filing gives the instructions below.

From its IRS Form 990-PF for tax year 2024.

Giving in 2024 was up from $3.2 million the year before.

48% of its 2024 grantees had not received a grant from it the year before, a sign it is open to new organizations.

Giving by year

Tax yearGrants paidNumber of grantsAssets
2023$3.2 million42$25,588
2024$3.2 million45$20,286

How to apply

ContactMEFN Selection Committee
921 Washington Ave S, Minneapolis, MN 55415-1257
Phone or email(612) 333-4220, neuro@mcknight.org
What to submit, deadlinesSee supplemental information
RestrictionsSee Supplemental Information

As written in the foundation's IRS filing for tax year 2024. Details may have changed since.

Foundation website IRS filings on ProPublica

What The McKnight Endowment Fund for Neuroscience funds

Where it gives

Its grants went to recipients in 17 states, the most to California.

StateGrantsAmount
California13$933,000
New York9$558,000
Massachusetts4$325,000
Illinois2$210,310
Utah2$175,000
New Jersey3$166,500
Florida2$150,000
Alabama1$100,000
Connecticut1$100,000
Michigan1$100,000

Grants paid in 2024

The 40 largest of 45 grants
RecipientPurposeAmount
Northwestern University
Chicago, IL
Funds Transferred from Van Andel. Regulation mechanism of thermosensitive receptors in nervous system. Principal Investigator: Juan Du, Ph.D.$110,310
Carnegie Mellon University
Pittsburgh, PA
Investigating Circuits and Mechanisms that Support Long-Lasting Recovery of Movement in Dopamine Depleted Mice. Principal Investigator: Aryn Gittis, Ph.D.$100,000
Fred Hutchinson Cancer Research Center
Seattle, WA
Adipocyte-brain mitochondrial signaling and its impacts on brain function. Principal Investigator: Akhila Rajan,Ph.D.$100,000
Mass General Brigham Incorporated
Boston, MA
The Neurobiology of Glioma: Understanding Malignant Neural Circuits Instructing Tumor Growth. Principal Investigator: Humsa Venkatesh,Ph.D.$100,000
Northwestern University Feinberg School of Medicine
Chicago, IL
Dissecting the Gut-brain Dynamics Underlying Anorexia. Principal Investigator: Lisa Beutler$100,000
Regents of the University of California
Berkeley, CA
Neurotensin mediated regulation of hedonic feeding behavior and obesity. Principal Investigator: Stephan Lammel Ph.D.$100,000
Regents of the University of California
Los Angeles, CA
Characterizing the Context: The Role of the Microenvironment in Shaping Human Glioblastoma. Principal Investigators: Aparna Bhaduri, Ph.D. and Kunal Patel, M.D.$100,000
Regents of the University of Michigan
Ann Arbor, MI
In vivo Reprogramming of Astrocytes into Neurons for Treating Parkinson's Disease. Principal Investigator: Thanh Hoang, Ph.D.$100,000
St Jude Children's Research Hospital
Memphis, TN
Identifying Brain Circuits that Connect Respiration and Cognitive State. Principal Investigator: Lindsey Schwarz$100,000
Stanford University School of Medicine
Palo Alto, CA
Neuron-to-OPC synapses in adaptive and maladaptive myelination. Principal Investigator: Juliet K. Knowles, MD, PhD$100,000
University of Alabama at Birmingham
Birmingham, AL
Leveraging Single-cell Epigenomics for Targeted Manipulation of Drug-activated Ensemble. Principal Investigator: Jeremy Day & Ian Maze$100,000
University of Utah
Salt Lake City, UT
Virus-Like Intercellular Transmission of Tau in Alzheimer's Disease. Principal Investigator: Jason Shepherd, Ph.D.$100,000
Yale University
New Haven, CT
Mechanism and functions of repeat expansion self-exonization in C9orf72 ALS/FTD. Principal Investigator: Junjie Guo, Ph.D.$100,000
Albert Einstein College of Medicine
New York, NY
Unravelling the mechanisms of synapse development, from molecules to behavior. Principal Investigator: Dr. Peri Kurshan$75,000
Columbia University in the City of New York
New York, NY
Skin-brain axis for rewarding touch behaviors. Principal Investigator: Dr. Ishmail Abdus-Saboor$75,000
Columbia University in the City of New York
New York, NY
Neural Mechanisms of Courtship and Monogamy. Principal Investigator: Dr. Vikram Gadagkar$75,000
Columbia University in the City of New York
New York, NY
Cortical circuits for perceiving visual form. Principal Investigator: Dr. Yasmine El-Shamayleh$75,000
Columbia University in the City of New York
New York, NY
Molecular Mechanisms of Intergenerational Memory. Principal Investigator: Bianca Jones Marlin, Ph.D.$75,000
Harvard Medical School
Boston, MA
Multiscale Neural Network Models to Infer Functional Motifs in the Brain. Principal Investigator: Kanaka Rajan, Ph.D.$75,000
Mass General Brigham Incorporated
Boston, MA
Development, Function, and Dysfunction of Somatosensory and Viscerosensory Systems in Autism Spectrum Disorder. Principal Investigator: Lauren Orefice, Ph.D.$75,000
Max Planck Florida Corporation
Jupiter, FL
Synaptic mechanisms and network dynamics underlying motor learning. Principal Investigator: Dr. Hidehiko Inagaki$75,000
New York University
New York, NY
Neural Circuit Mechanisms of Inference. Principal Investigator: Christine Constantinople, Ph.D$75,000
New York University
New York, NY
Modulation of striatal cells and synapses by dopamine movement signals. Principal Investigator: Dr. Tanya Sippy$75,000
Oregon Health & Science University
Portland, OR
Mechanosensation for guiding cellular morphology. Principal Investigator: Dr. Swetha Murthy$75,000
Regents of the University of California
Berkeley, CA
Evolution of neural diversity and patterning in the visual system. Principal Investigator: Dr. Karthik Shekhar$75,000
Regents of the University of California
Berkeley, CA
Illuminating Oxytocin Signaling in the Brain with Near-Infrared Fluorescent Nanosensors. Principal Investigator: Markita Landry, Ph.D.$75,000
Regents of the University of California
Berkeley, CA
The Molecular Basis of Psychedelic-Induced Plasticity. Principal Investigator: Andrea Gomez, Ph.D.$75,000
Regents of the University of California
Santa Barbara, CA
Neural Representation of The World During Navigation. Principal Investigator: Sung Soo Kim, Ph.D.$75,000
Scripps Research Institute
La Jolla, CA
Neural Population Dynamics Mediating the Balance of Competing Survival Needs. Principal Investigator: Ann Kennedy, Ph.D.$75,000
Scripps Research Institute
La Jolla, CA
In vivo Neurogenomics at Scale. Principal Investigator: Xin Jin, Ph.D.$75,000
The Board of Trustees of the Leland Stanford Junior University
Stanford, CA
Machine Learning Methods for Discovering Structure in Neural and Behavioral Data. Principal Investigator: Dr. Scott Linderman$75,000
The Board of Trustees of the Leland Stanford Junior University
Stanford, CA
How Does 3D Genome Architecture Shape the Development and Aging of the Brain?. Principal Investigator: Longzhi Tan, Ph.D.$75,000
Trustees of Princeton University
Princeton, NJ
Proportional-Integral Feedback in a Biological 'Gyroscope'. Principal Investigator: Bradley Dickerson, Ph.D.$75,000
Trustees of Princeton University
Princeton, NJ
Computational Neuroendocrinology: Linking Hormone-Mediated Transcription to Complex Behavior Through Neural Dynamics. Principal Investigator: Annegret Falkner, Ph.D.$75,000
University of Florida
Gainesville, FL
Neural Mechanisms of Shifts Between Social Competition and Cooperation. Principal Investigator: Nancy Padilla-Coreano, Ph.D.$75,000
University of New Mexico
Albuquerque, NM
Molecular Mechanisms Regulating Neural Diversity: From Stem Cells to Circuits. Principal Investigator: Mubarak Hussain Syed, Ph.D.$75,000
University of Utah
Salt Lake City, UT
Neuropeptidergic Cortical Control of Social Isolation. Principal Investigator: Dr. Moriel Zelikowsky$75,000
UT Southwestern Medical Center
Dallas, TX
Understanding the Construction and Function of Glycinergic Post-Synaptic Assemblies. Principal Investigator: Weiwei Wang, Ph.D.$75,000
Whitehead Institute for Biomedical Research
Cambridge, MA
Molecular Anatomy of Hibernation Circuits. Principal Investigator: Sinisa Hrvatin, Ph.D.$75,000
New York University Grossman School of Medicine
New York, NY
McKnight Pecot Fellowship 2024. Principal Investigator: Buyong Kim$16,500

Officers and trustees

As listed in Part VIII of the 2024 filing.

Questions people ask

Does The McKnight Endowment Fund for Neuroscience accept grant applications?

Yes. Its latest IRS filing says it accepts applications, with this on deadlines: See supplemental information.

How much does The McKnight Endowment Fund for Neuroscience give?

$3.2 million in tax year 2024, across 45 grants, with a typical grant of $75,000.

Who runs The McKnight Endowment Fund for Neuroscience?

Its 2024 filing lists Dana Anderson (Director), Stephanie Duffy (Secretary/Treasurer), Catherine Dulac (Director) and Michael D Ehlers MD PhD (Director) among 11 officers and trustees.

What does The McKnight Endowment Fund for Neuroscience fund?

Based on its grants, mainly education, health and science and research.

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